The Frailty Working Group engages in scientific discussion, project planning, manuscript development, and funding strategies related to frailty science. A core group of researchers from multiple disciplines (including geriatrics, cardiology, biostatistics, epidemiology, endocrinology, infectious diseases, and mental health) at Johns Hopkins and beyond convenes twice a month to envision, develop, and advance research on important questions about the etiology, measurement, and amelioration of frailty, its consequences, and the translation of effective strategies into clinical practice.