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Aging and Health

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JHU OAIC Publications, by year
2014 -2013 - 2012 - 2011- 2010-2009- 2008- 2007- 2006- 2005- 2004


2014

Langdon JM, Yates SC, Femnou LK, McCranor GJ, Cheadle C, Xue QL, Vaulont S, Civin CI, Walston JD, Roy CN. Hepcidin-dependent and hepcidin-independent regulation of erythropoiesis in a mouse model of anemia of chronic inflammation. Am J Hematol. 2014 Jan 11. doi: 10.1002/ajh.23670. [Epub ahead of print] PMID: 24415655.

Matteini AM1, Li J, Lange EM, Tanaka T, Lange LA, Tracy RP, Wang Y, Biggs ML, Arking DE, Fallin MD, Chakravarti A, Psaty BM, Bandinelli S, Ferrucci L, Reiner AP, Walston JD. Novel gene variants predict serum levels of the cytokines IL-18 and IL-1ra in older adults. Cytokine. 2014 Jan;65(1):10-6. doi: 10.1016/j.cyto.2013.10.002. Epub 2013 Oct 29.  PMID: 24182552.

Varadhan R, Xue QL, Bandeen-Roche K. Semicompeting risks in aging research: methods, issues and needs.  Lifetime Data Anal. 2014 Apr 12. [Epub ahead of print].  PMID: 24729136

2013

Akki A, Yang H, Gupta A, Chacko VP, Yano T, Leppo MK, Steenbergen C, Walston J, Weiss RG. Skeletal muscle ATP kinetics are impaired in frail mice.  Age (Dordr). 2013 May 22. [Epub ahead of print].  PMID: 23695949. PMCID: PMC3889887

Corriere M, Rooparinesingh N, Kalyani RR. Epidemiology of diabetes and diabetes complications in the elderly: an emerging public health burden. Curr Diab Rep. 2013 Dec;13(6):805-13. doi: 10.1007/s11892-013-0425-5. PMID: 24018732. PMCID: PMC3856245.

Davalos-Bichara M, Lin FR, Carey JP, Walston JD, Fairman JE, Schubert MC, Barron JS, Hughes J, Millar JL, Spar A, Weber KL, Ying HS, Zackowski KM, Zee DS, Agrawal Y. Development and validation of a falls-grading scale. J Geriatr Phys Ther. 2013 Apr-Jun;36(2):63-7. doi: 10.1519/JPT.0b013e31825f6777.  PMID: 22810170 [PubMed - indexed for MEDLINE] PMCID: PMC3867809

Fried LP, Carlson MC, McGill S, Seeman T, Xue QL, Frick K, Tan E, Tanner EK, Barron J, Frangakis C, Piferi R, Martinez I, Gruenewald T, Martin BK, Berry-Vaughn L, Stewart J, Dickersin K, Willging PR, Rebok GW. Experience Corps: a dual trial to promote the health of older adults and children's academic success. Contemp Clin Trials. 2013 Sep;36(1):1-13. doi: 10.1016/j.cct.2013.05.003. Epub 2013 May 13. PMID: 23680986.

Kalyani RR, Tra Y, Yeh HC, Egan JM, Ferrucci L, Brancati FL. Quadriceps strength, quadriceps power, and gait speed in older U.S. adults with diabetes mellitus: results from the National Health and Nutrition Examination Survey, 1999-2002. J Am Geriatr Soc. 2013 May;61(5):769-75. doi: 10.1111/jgs.12204. Epub 2013 Apr 25. PMID: 23617584.  PMCID: PMC3725774.

McAdams-Demarco MA, Suresh S, Law A, Salter ML, Gimenez LF, Jaar BG, Walston JD, Segev DL. Frailty and falls among adult patients undergoing chronic hemodialysis: a prospective cohort study. BMC Nephrol. 2013 Oct 16;14(1):224. [Epub ahead of print]  PMID: 24131569.  PMCID: PMC3852906.

McAdams-DeMarco MA, Law A, Salter ML, Boyarsky B, Gimenez L, Jaar BG, Walston JD, Segev DL. Frailty as a novel predictor of mortality and hospitalization in individuals of all ages undergoing hemodialysis. J Am Geriatr Soc. 2013 Jun;61(6):896-901. doi: 10.1111/jgs.12266. Epub 2013 May 27. PMID: 23711111. PMCID: PMC3938084

McAdams-MeMarco MA, Law A, Salter ML, Chow E, Grams M, Walston J, Segev DL. Frailty and early hospital readmission after kidney transplantation. Am J Transplant. 2013 Aug;13(8):2091-5. doi: 10.1111/ajt.12300. Epub 2013 June 3. PMID 23731461.

McCranor BJ, Langdon JM, Prince OD, Femnou LK, Berger AE, Cheadle C, Civin CI, Kim A, Rivera S, Ganz T, Vaulont S, Xue QL, Walston JD, Roy CN. Investigation of the role of interleukin-6 and hepcidin antimicrobial peptide in the development of anemia with age. Haematologica. 2013 Oct;98(10):1633-40. doi: 10.3324/haematol.2013.087114. Epub 2013 Aug 30. PMID: 23996485.  PMCID: PMC3789470.

Sikka G, Miller K, Jung S, Fraser III CD, Ellis C, Ross D, Vandegaer K, Bedja D, Gabrielson K, Walston JD, Berkowitz DE, Barouch LA. Interleukin 10 Knockout Frail Mice Develop Cardiac and Vascular Dysfunction with Increased Age. Exp Gerontol 2013 Feb;48(2):128-35. doi: 10.1016/j.exger.2012.11.001. Epub 2012 Nov 13. PMID: 23159957. PMCID: PMC3744178.

Varadhan R, Yao W, Matteini A, Beamer BA, Xue QL, Yang H, Manwani B, Reiner A, Jenny N, Parekh N, Fallin MD, Newman A, Bandeen-Roche K, Tracy R, Ferrucci L, Walston J. Simple Biologically Informed Inflammatory Index of Two Serum Cytokines Predicts 10 Year All-Cause Mortality in Older Adults. J Gerontol A Biol Sci Med Sci glt023 first published online May 20, 2013 doi:10.1093/gerona/glt023. PMID: 23689826.

Yasar S, Xia J, Yao W, Furberg CD, Xue QL, Mercado CI, Fitzpatrick AL, Fried LP, Kawas CH, Sink KM, Williamson JD,DeKosky ST, Carlson MC; Ginkgo Evaluation of Memory (GEM) Study Investigators.Antihypertensive drugs decrease risk of Alzheimer disease: Ginkgo Evaluation of Memory Study. Neurology. 2013 Sep 3;81(10):896-903. doi: 10.1212/WNL.0b013e3182a35228. Epub 2013 Aug 2. PMCID: PMC3885216.

2012

Abadir PM, Walston JD, Carey RM. Subcellular characteristics of functional intracellular renin-angiotensin systems. Peptides. 2012 Dec;38(2):437-45. doi: 10.1016/j.peptides.2012.09.016. Epub 2012 Sep 29. PubMed PMID: 23032352. PMCID: PMC3770295.

Agrawal Y, Bremova T, Kremmyda O, Strupp M. Semicircular canal, saccular and utricular function in patients with bilateral vestibulopathy: analysis based on etiology.  J Neurol. 2012 Oct 27. [Epub ahead of print]. PMID: 23104126.

Agrawal Y, Zuniga MG, Davalos-Bichara M, Schubert MC, Walston JD, Hughes J, Carey JP. Decline in semicircular canal and otolith function with age. Otol Neurotol. 2012 Jul;33(5):832-9. PMCID: PMC3376350.

Andres-Mateos E, Mejias R, Soleimani A, Lin BM, Burks TN, Marx R, Lin B, Zellars RC, Zhang Y, Huso DL, Marr TG, Leinwand LA, Merriman DK, Cohn RD. Impaired skeletal muscle regeneration in the absence of fibrosis during hibernation in 13-lined ground squirrels. PLoS One. 2012;7(11):e48884. doi: 10.1371/journal.pone.0048884. Epub 2012 Nov 14. PMID: 23155423 [PubMed - in process] PMCID: PMC3498346.

Chang SS, Weiss CO, Xue QL, Fried LP. Association between inflammatory-related disease burden and frailty: results from the Women's Health and Aging Studies (WHAS) I and II. Arch Gerontol Geriatr. 2012 Jan;54(1):9-15. Epub 2011 Jul 16. PMID: 21763008. PMCID: PMC3197795.

Davalos-Bichara M, Schubert MC, Walston JD, Hughes J, Carey JP, Zackowski KM, Zee DS, Agrawal Y. Development and validation of a falls grading scale. J Geriatric Phys Ther. 2012 Jul 17. [Epub ahead of print] PMID: 22810170.

Garonzik-Wang JM, Govindan P, Grinnan JW, Liu M, Ali HM, Chakraborty A, Jain V, Ros RL, James NT, Kucirka LM, Hall EC, Berger JC, Montgomery RA, Desai NM, Dagher NN, Sonnenday CJ, Englesbe MJ, Makary MA, Walston JD, Segev DL. Frailty and delayed graft function in kidney transplant recipients. Arch Surg. 2012 Feb;147(2):190-3. PMID: 22351919.

Giovannetti ER, Wolff JL, Xue QL, Weiss CO, Leff B, Boult C, Hughes T, and Boyd CM. Difficulty with health care tasks among caregivers of multimorbid older adults. J Gen Intern Med. 2012 Jan;27(1):37-44. PMID: 21874385. PMCID: PMC3250537.

Kalyani RR, Tian J, Xue Q, Walston JW, Cappola AR, Fried LP, Brancati FL, Blaum CS. Hyperglycemia and Incidence of Frailty and Lower Extremity Mobility Limitations in Older Women. J Am Geriatr Soc. 2012 Aug 10. doi: 10.1111/j.1532-5415.2012.04099.x. [Epub ahead of print] PMID: 22882211.

Kalyani RR, Varadhan R, Weiss CO, Fried LP, Cappola A. Frailty Status and Altered Dynamics of Circulating Energy Metabolism Hormones After Oral Glucose in Older Women. The Journal of Nutrition, Health & Aging 2012 June 25, DOI: 10.1007/s12603-012-0066-4 [online first ahead of print].

Kalyani RR, Metter EJ, Ramachandran R, Chia CW, Saudek CD, Ferrucci L. Glucose and Insulin Measurements From the Oral Glucose Tolerance Test and Relationship to Muscle Mass. J Gerontol A Biol Sci Med Sci. 2012 Jan;67(1):74-81. Epub 2011 Feb 24. PMID: 21350243. PMCID: PMC3260481.

Ko F, Yu Q, Xue QL, Yao W, Brayton C, Yang H, Fedarko N, Walston J. Inflammation and mortality in a frail mouse model. Age (Dordr). 2012 Jun; 34(3):705-15. Epub 2011 June 2. PMID:21633802. PMCID: PMC3337927.

Lin FR, Ferrucci L. Hearing loss and falls among older adults in the United States. Arch Intern Med. 2012 Feb 27;172(4):369-71. PMID:22371929 [PubMed - in process] PMCID: PMC3518403.

McAdams-Demarco MA, Law A, Garonzik-Wang JM, Gimenez L, Jaar BG, Walston JD, Segev DL. Activity of daily living disability and dialysis mortality: better prediction using metrics of aging. J Am Geriatr Soc. 2012 Oct;60(10):1981-2. doi: 10.1111/j.1532-5415.2012.04161.x. PubMed PMID: 23057455.

Mielke MM, Bandaru VV, Haughey NJ, Xia J, Fried LP, Yasar S, Albert M, Varma V, Harris G, Schneider EB, Rabins PV, Bandeen-Roche K, Lyketsos CG, Carlson MC. Serum ceramides increase the risk of Alzheimer disease: the Women's Health and Aging Study II. Neurology. 2012 Aug 14;79(7):633-41. doi: 10.1212/WNL.0b013e318264e380. Epub 2012 Jul 18. PMID: 22815558 [PubMed - indexed for MEDLINE] PMCID: PMC3414665.

Mielke MM, Okonkwo OC, Oishi K, Mori S, Tighe S, Miller MI, Ceritoglu C, Brown T, Albert M, Lyketsos CG. Fornix integrity and hippocampal volume predict memory decline and progression to Alzheimer's disease. Alzheimers Dement. 2012;8(2):105-13. doi: 10.1016/j.jalz.2011.05.2416. PMID: 22404852 [PubMed - indexed for MEDLINE] PMCID: PMC3305232.

Prince OD, Langdon JM, Layman AJ, Prince IC, Sabogal M, Mak HH, Berger AE, Cheadle C, Chrest FJ, Yu Q, Andrews NC, Xue QL, Civin CI, Walston JD, Roy CN. Late stage erythroid precursor production is impaired in mice with chronic inflammation. Haematologica. 2012 Nov;97(11):1648-56. doi: 10.3324/haematol.2011.053397. Epub 2012 May 11. PMID: 22581006. PMCID: PMC3487436.

Roy CN, Semba RD, Sun K, Bandinelli S, Varadhan R, Patel KV, Guralnik JM, Ferrucci L. Circulating selenium and carboxymethyl-lysine, an advanced glycation endproduct, are independent predictors of anemia in older community-dwelling adults. Nutrition. 2012 Feb 9. [Epub ahead of print] PMID:22325035. PMCID: PMC3377823.

Talegawkar SA, Bandinelli S, Bandeen-Roche K, Chen P, Milaneschi Y, Tanaka T, Semba RD, Guralnik JM, Ferrucci L. A higher adherence to a Mediterranean-style diet is inversely associated with the development of frailty in community-dwelling elderly men and women. J Nutr. 2012 Dec;142(12):2161-6. doi: 10.3945/jn.112.165498. Epub 2012 Oct 24. PMID: 23096005. PMCID: PMC3497964.

Tighe SK, Oishi K, Mori S, Smith GS, Albert M, Lyketsos CG, Mielke MM. Diffusion tensor imaging of neuropsychiatric symptoms in mild cognitive impairment and Alzheimer's dementia. J Neuropsychiatry Clin Neurosci. 2012 Fall;24(4):484-8. doi: 10.1176/appi.neuropsych.11120375. PMID: 23224456 [PubMed - in process] PMCID: PMC3533244.

Walston JD. Sarcopenia in older adults. Curr Opin Rheumatol. 2012 Nov;24(6):623-7. PubMed PMID: 22955023.

Wang GC, Dash P, McCullers JA, Doherty PC, Thomas PG. T Cell Receptor αβ Diversity Inversely Correlates with Pathogen-Specific Antibody Levels in Human Cytomegalovirus Infection. Sci Transl Med 4 April 2012: Vol. 4, Issue 128, p. 128ra42. DOI: 10.1126/scitranslmed.3003647. PMC Journal- In Process.

Xue QL, Bandeen-Roche K, Mielenz, TJ, Seplaki CL, Szanton SL, Thorpe RJ, Kalyani RR, Chaves PH, Dam TT, Ornstein K, RoyChoudhury A, Yao WL, Fried LP. Patterns of 12-Year Change in Physical Activity in Community-Dwelling Older Women: Can Modest Levels of Physical Activity Help Older Women Live Longer? Am J Epidemiol. 2012 Aug 30. [Epub ahead of print] PMID: 22935515.

Zhang T, Hwang HY, Hao H, Talbot C Jr, Wang J. Caenorhabditis elegans RNA-processing Protein TDP-1 Regulates Protein Homeostasis and Lifespan. J Biol Chem. 2012 Jan 9. [Epub ahead of print]. PMID:22232551. PMCID: PMC3318719.

Zuniga MG, Dinkes RE, Davalos-Bichara M, Carey JP, Schubert MC, King WM, Walston J, Agrawal Y. Association Between Hearing Loss and Saccular Dysfunction in Older Individuals. Otol Neurotol. 2012 Dec;33(9):1586-92. doi: 10.1097/MAO.0b013e31826bedbc. 2012 Oct 11. [Epub ahead of print]. PMID: 23064383. PMCID: PMC3498596.

2011

Abadir PM, Foster DB, Crow M, Cooke CA, Rucker JJ, Jain A, Smith BJ, Burks TN, Cohn RD, Fedarko NS, Carey RM, O'Rourke B, Walston JD. Identification and characterization of a functional mitochondrial angiotensin system. Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14849-54. Epub 2011 Aug 18. PMID:21852574. PMCID: PMC3169127.

Abadir PM. The frail renin-angiotensin system. Clin Geriatr Med. 2011 Feb;27(1):53-65. PMID:21093722.

Abadir PM, Walston JD, Carey RM, Siragy HM. Angiotensin II Type-2 Receptors Modulate Inflammation Through Signal Transducer and Activator of Transcription Proteins 3 Phosphorylation and TNF? Production. J Interferon Cytokine Res. 2011 Feb 2. [Epub ahead of print]. PMID: 21288138. PMCID: PMC3104285.

Agbedia OO, Varma VR, Seplaki CL, Seeman TE, Fried LP, Li L, Harris GC, Rebok GW, Xue QL, Tan EJ, Tanner E, Parisi JM, McGill S, Carlson MC. Blunted diurnal decline of cortisol among older adults with low socioeconomic status. Ann N Y Acad Sci. 2011 Aug;1231(1):56-64. doi: 10.1111/j.1749-6632.2011.06151.x. PMID:21884161. PMCID: PMC3369216.

Benke KS, Carlson MC, Doan BQ, Walston JD, Xue QL, Reiner AP, Fried LP, Arking DE, Chakravarti A, Fallin MD. The association of genetic variants in interleukin-1 genes with cognition: Findings from the cardiovascular health study. Exp Gerontol. 2011 Dec; 46(12):1010-9. Epub Sep 24. PMID:21968104.

Burks TN, Cohn RD. One size may not fit all: anti-aging therapies and sarcopenia. Aging (Albany NY). 2011 Dec;3(12):1142-53. PMID: 22184279. PMCID: PMC3273894.

Burks TN and Cohn RD. Role of TGF-b signaling in inherited and acquired myopathies. Skeletal Muscle. 2011 May 4;1(1):19. PMID:21798096. PMCID: PMC3156642.

Burks TN, Andres-Mateo, E. Marx R, Mejias R. Van Erp C, Simmers JL, Walston JD, Ward CW, Cohn RD. Losartan restores skeletal muscle remodeling and protects against disuse atrophy in sarcopenia. Sci Trans Med. 2011 May 11;3(82):82ra37. PMID:21562229. PMCID: PMC3140459.

Calvi CL, Podowski M, D'Alessio FR, Metzger SL, Misono K, Poonyagariyagorn H, Lopez-Mercado A, Ku T, Lauer T, Cheadle C, Talbot CC Jr, Jie C, McGrath-Morrow S, King LS, Walston J, Neptune ER. Critical transition in tissue homeostasis accompanies murine lung senescence. PLoS One. 2011;6(6):e20712. Epub 2011 Jun 21. PMID:21713037. PMCID: MPC3119663.

Eckel SP, Bandeen-Roche K, Chaves PH, Fried LP, Louis TA. Surrogate screening models for the low physical activity criterion of frailty. Aging Clin Exp Res. 2011 Jun;23(3):209-16. PMID: 21993168. PMCID: PMC3351838.

Ho YY, Matteini AM, Beamer BA, Fried LP, Xue Q-L, Arking DE, Chakravarti A, Walston JD, Fallin D. Exploring Biologically Relevant Pathways in Frailty. J Gerontol A Biol Sci Med Sci. 2011 September;66A(9):975–979. PMID: 21743092. PMCID: PMC3156628.

Kalyani RR, Varadhan R, Weiss CO, Fried LP, Cappola A. Frailty Status and Altered Glucose-Insulin Dynamics. Journal of Gerontology: Medical Sciences. 2011; 26 August [epub ahead of print] PMID: 21873592.

Leng SX, Tian X, Matteini A, Li H, Hughes J, Jain A, Walston JD, Fedarko NS. IL-6-independent association of elevated serum neopterin levels with prevalent frailty in community-dwelling older adults. Age Ageing. 2011 Jul;40(4):475-81. Epub 2011 May 17. PMID: 21586579. PMCID: PMC3114624.

Leng SX, Qu T, Semba RD, Li H, Yao X, Nilles T, Yang X, Manwani B, Walston JD, Ferrucci L, Fried LP, Margolick JB, Bream JH. Relationship between cytomegalovirus (CMV) IgG serology, detectable CMV DNA in peripheral monocytes, and CMV pp65(495-503)-specific CD8 (+) T cells in older adults. Age (Dordr). 2011 Dec; 33(4):607-14. Epub 2011 Jan 28. PMID: 21274637. PMCID: PMC3220402

Leng SX, Li HF, Xue Q-L, Yao X, Tian J, Yang X, Ferrucci L, Fedarko N, Fried LP, Semba RD. Association of detectable cytomegalovirus (CMV) DNA in monocytes rather than positive CMV IgG serology with elevated neopterin levels in community-dwelling older adults. Exp Gerontol2011 Aug;46(8):679-84. Epub 2011 Apr 13. PMID: 21513787. PMCID: PMC31314158.

Lin FR, Thorpe R, Gordon-Salant S, Ferrucci L. Hearing Loss Prevalence and Risk Factors Among Older Adults in the United States. J Gerontol A Biol Sci Med Sci. 2011 May;66(5):582-90. Epub 2011 Feb 27. PMID: 21357188. PMCID: PMC3074958

Leoutsakos JM, Bandeen-Roche K, Garrett-Mayer E, Zandi PP. Incorporating scientific knowledge into phenotype development: Penalized latent class regression. Stat Med. 2011 Mar 30;30(7):784-98. PMID: 21394753.

Moseley KF, Dobrosielski DA, Stewart Kj, Jan De Beur SM, Sellmeyer DE. Lean mass and fat mass predict bone mineral density in middle-aged individuals with non-insulin -requiring type 2 diabetes mellitus. Clin Endocrinol (Oxf). 2011 May;74(5):565-71. doi: 10.1111/j.1365-2265.2010.03965.x. Epub 2010 Dec 24.

Neufeld KJ, Joseph Bienvenu O, Rosenberg PB, Mears SC, Lee HB, Kamdar BB, Sieber FE, Krumm SK, Walston JD, Hager DN, Touradji P, Needham DM. The Johns Hopkins Delirium Consortium: a model for collaborating across disciplines and departments for delirium prevention and treatment. J Am Geriatr Soc. 2011 Nov;59 Suppl 2:S244-8. doi: 10.1111/j.1532-5415.2011.03672.x. PMID:22091568[PubMed - indexed for MEDLINE]. PMC Journal- In Process.

Reinke C, Bevans-Fonti S, Grigoryev DN, Drager LF, Myers AC, Wise RA, Schwartz AR, Mitzner W, Polotsky VY. Chronic intermittent hypoxia induces lung growth in adult mice. Am J Physiol Lung Cell Mol Physiol. 2011 Feb;300(2):L266-73. Epub 2010 Dec 3. PMID:21131398. PMCID: PMC3043819.

Roy CN. Anemia in frailty. Clin Geriatr Med. 2011 Feb;27(1):67-78. PMID:21093723. PMCID: PMC2998908.

Szanton SL, Thorpe RJ, Boyd C, Tanner EK, Leff B, Agree E, Xue QL, Allen JK, Seplaki CL, Weiss C, Guralnik JM, Gitlin LN. CAPABLE: A bio-behavioral-environmental intervention to improve function and health-related quality of life in disabled, older adults. J Am Geriatr Soc. 2011 Dec;59(12):2314-20. PMID: 22091738. PMCID: PMC3245364.

Walston JD. Frailty. Preface. Clin Geriatr Med. 2011 Feb;27(1):xi. No abstract available. PMID:21093717.

Weiss CO. Frailty and chronic diseases in older adults. Clin Geriatr Med. 2011 Feb;27(1):39-52. Review. PMID:21093721.

Xue QL. The frailty syndrome: definition and natural history. Clin Geriatr Med. 2011 Feb;27(1):1-15. Review. PMID:21093718. PMCID: PMC3028599.

Xue Q-L, Walston JD, Fried LP, Beamer BA. Prediction of risk of falling, physical disability, and frailty by rate of decline in grip strength: The Women’s Health and Aging Study. Arch Intern Med. 2011 Jun 27;171(12):1119-21. No abstract available. PMID:21709116.

Yao X, Hamilton R, Weng N-P, Xue Q-L, Bream JH, Tian J, Yeh S-H, Resnick B, Xu XY, Walston JD, Fried LP, Leng SX. Frailty is associated with poor vaccine-induced antibody response and increased influenza infection in community-dwelling older adults. Vaccine. 2011 Jul 12;29(31):5015-21. Epub 2011 May 10. PMID:21565245. PMCID: PMC3129421.

Yao X, Li H, Leng SX. Inflammation and immune system alterations in frailty. Clin Geriatr Med. 2011 Feb;27(1):79-87. PMID: 21093724. PMCID: PMC3011971.

Zhang T, Mullane PC, Periz G, Wang J. TDP-43 neurotoxicity and protein aggregation modulated by heat shock factor and insulin/IGF-1 signaling. Hum Mol Genet. 2011 May 15; 20(10):1952-65. Epub 2011 Feb 25. PMID: 21355045. PMCID: PMC3080607.

2010

Crentsil V. Mechanistic contribution of carnitine deficiency to geriatric frailty. Ageing Res Rev. 2010 Jul;9(3):265-8. Epub 2010 Mar 17. PMID: 20223299.

Crentsil V, Ricks MO, Xue QL, Fried LP. A pharmacoepidemiologic study of community-dwelling, disabled older women: Factors associated with medication use. Am J Geriatr Pharmacother. 2010 Jun;8(3):215-24. PMID: 20624611.

Franckowiak SC, Dobrosielski DA, Reilley SM, Walston JD, Andersen RE. Maximal Heart Rate Prediction in Adults that are Overweight or Obese. J Strength Cond Res. 2010 Nov 24. [Epub ahead of print]. PMID: 21116203.

Makary MA, Segev DL, Fried LP, Syin D, Bandeen-Roche K, Patel P, Devgan L, Holzmueller CG, Tian J, Pronovost PR. Frailty as a Predictor of Surgical Outcome in Older Patients. J Am Coll Surg. 2010 Jun;210(6):901-8. Epub 2010 Apr 28. PMID: 20510798.

Matteini AM, Walston JD, Bandeen-Roche K, Arking DE, Allen RH, Fried LP, Chakravarti A, Stabler SP, Fallin MD.  Transcobalamin-II variants, decreased vitamin B12 availability and increased risk of frailty.  J Nutr Health Aging. 2010 Jan;14(1):73-7.  PMID: 20082058.

Matteini AM, Fallin MD, Kammerer CM, Schupf N, Yashin AI, Christensen K, Arbeev KG, Barr G, Mayeux R, Newman AB, Walston JD. Heritability Estimates of Endophenotypes of Long and Health Life: The Long Life Family Study. J Gerontol A Biol Sci Med Sci. 2010 Sep 2. [Epub ahead of print]. PMID: 20813793

Moore AZ, Biggs ML, Matteini AM, O’Connor A, McGuire S, Beamer B, Fallin MD, Fried LP, Walston J, Chakravarti A, Arking DE. Polymorphisms in the mitochondrial DNA control region and frailty in older adults.  PLoS One. 2010 Jun 10;5(6):e11069. PMID: 20548781. PMCID: PMC2883558.

Rosenberg PB, Mielke MM, Xue QL, Carlson MC.  Depressive symptoms predict incident cognitive impairment in cognitive healthy older women.  Am J Geriatr Psychiatry. 2010 Mar;18(3):204-11.  PMID: 20224517.

Roy CN.  Anemia of inflammation.  Hematology Am Soc Hematol Educ Program. 2010;2010:276-80. PMID: 21239806.

Semba RD, Patel KV, Ferrucci L, Sun K, Roy CN, Guralnik JM, Fried LP. Serum antioxidants and inflammation predict red cell distribution width in older women: The Women's Health and Aging Study I. Clin Nutr. 2010 Oct;29(5):600-4. 2010 Mar 22. [Epub ahead of print] PMID: 20334961

Sourial N, Wolfson C, Bergman H, Zhu B, Karunananthan S, Quail J, Fletcher J, Weiss D, Bandeen-Roche K, Béland F. A correspondence analysis revealed frailty deficits aggregate and are multidimensional. J Clin Epidemiol. 2010 Jun;63(6):638-46. Epub 2009 Nov 6.

Sourial N, Wolfson C, Zhu B, Quail J, Fletcher J, Karunananthan S, Bandeen-Roche K, Béland F, Bergman H. Correspondence analysis is a useful tool to uncover the relationships among categorical variables. J Clin Epidemiol. 2010 Jun;63(6):647-54. Epub 2009 Oct 31.

Tanaka T, Roy CN, Yao W, Matteini A, Semba RD, Arking D, Walston JD, Fried LP, Singleton A, Guralnik J, Abecasis GR, Bandinelli S, Longo DL, and Ferrucci L. A Genome-Wide Association Analysis of Serum Iron Concentrations. Blood 2010; 115(1):94-96. PMID: 19880490

Varadhan R, Weiss CO, Segal JB, Wu AW, Scharfstein D, Boyd C. Evaluating health outcomes in the presence of competing risks: a review of statistical methods and clinical applications. Med Care. 2010 Jun;48(6 Suppl):S96-105. PMID: 20473207

Wang GC, Talor MV, Rose NR, Cappola AR, Chiou RB, Weiss C, Walston JD, Fried LP, Caturegli P. Thyroid autoantibodies are associated with a reduced prevalence of frailty in community-dwelling older women. J Clin Endocrinol Metab. 2010 Mar;95(3):1161-8. Epub 2010 Jan 8.  PMID: 20061418.

Wang GC, Kao WH, Murakami P, Xue QL, Chiou RB, Detrick B, McDyer JF, Semba RD, Casolaro V, Walston JD, Fried LP. Cytomegalovirus Infection and the Risk of Mortality and Frailty in Older Women: A Prospective Observational Cohort Study. Am J Epidemiol. 2010 May 15;171(10):1144-52. Epub 2010 Apr 16. PMID: 20400465.

Weiss CO, Hoenig HH, Varadhan R, Simonsick EM, Fried LP. Relationships of cardiac, pulmonary, and muscle reserves and frailty to exercise capacity in older women. J Gerontol A Biol Sci Med Sci. 2010 Mar;65(3):287-94. Epub 2009 Oct 12. PMID: 19822621.

Xue QL, Beamer BA, Chaves PH, Guralnik JM, Fried LP. Heterogeneity in rate of decline in grip, hip, and knee strength and the risk of all-cause mortality: the Women's Health and Aging Study II.J Am Geriatr Soc. 2010 Nov;58(11):2076-84. PMID:21054287

2009

Alipanah N, Varadhan R, Sun K, Ferrucci L, Fried LP, Semba RD. Low serum carotenoids are associated with a decline in walking speed in older women. J Nutr Health Aging. 2009 Mar;13(3):170-5. PMID: 19262947.

Bandeen-Roche K, Walston JD, Huang Y, Semba RD, Ferrucci L. Measuring systemic inflammatory regulation in older adults: evidence and utility. Rejuvenation Res. 2009 Dec;12(6):403-10. PMID: 20041734

Boyd C, Ricks M, Fried LP, Guralnik JM, Xue Q-L, Xia J, Bandeen-Roche K. Functional Decline And Recovery of Activities of Daily Living among Hospitalized, Disabled Older Women: The Women’s Health and Aging Study I. J Am Geriatr Soc. 2009 Aug 20. [Epub ahead of print]. PMID: 19694869

Cappola AR, Xue QL, Fried LP. Multiple hormonal deficiencies in anabolic hormones are found in frail older women: the Women's Health and Aging studies. J Gerontol A Biol Sci Med Sci. 2009 Feb;64(2):243-8. Epub 2009 Jan 31. PMID: 19182229

Carlson MC, Xue QL, Zhou J, & Fried LP. Executive Decline and Dysfunction Precedes Declines in Memory: The Women's Health and Aging Study II. J Gerontol A Biol Sci Med Sci. 2009 Jan;64(1):110-7. Epub 2009 Jan 31. PMID: 19182230.

Carlson MC, Erickson KI, Kramer AF, Voss MW, Bolea N, Mielke M, McGill S, Rebok GW, Seeman T, Fried LP. Evidence for neurocognitive plasticity in at-risk older adults: the experience corps program. J Gerontol A Biol Sci Med Sci. 2009 Dec;64(12):1275-82. Epub 2009 Aug 19. PMID: 19692672

Chang SS, Weiss CO, Xue QL, Fried LP. Patterns of comorbid inflammatory diseases in frail older women: the Women's Health and Aging Studies I and II. J Gerontol A Biol Sci Med Sci. 2010 Apr;65(4):407-13. Epub 2009 Nov 23. PMID: 19933749.

Deal JA, Carlson MC, Xue QL, Fried LP, Chaves PH. Anemia and 9-year domain-specific cognitive decline in community-dwelling older women: The Women's Health and Aging Study II. J Am Geriatr Soc. 2009 Sep;57(9):1604-11. Epub 2009 Aug 13. PMID: 19682133.

Ferrucci L, Perry JR, Matteini A, Perola M, Tanaka T, Silander K, Rice N, Melzer D, Murray A, Cluett C, Fried LP, Albanes D, Corsi AM, Cherubini A, Guralnik J, Bandinelli S, Singleton A, Virtamo J, Walston J, Semba RD, Frayling TM. Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study. Am J Hum Genet. 2009 Feb;84(2):123-33. Epub 2009 Jan 29. PMID: 19185284.

Fallin MD, Matteini A. Genetic Epidemiology in Aging Research. class="journalname"J Gerontol A Biol Sci Med Sci. 2009 Jan;64(1):47-60. Epub 2009 Jan 23. PMID: 19168782.

Fried LP, Xue QL, Cappola AR, Ferrucci L, Chaves P, Varadhan R, Guralnik JM, Leng SX, Semba RD, Walston JD, Blaum CS, Bandeen-Roche K. Nonlinear multisystem physiological dysregulation associated with frailty in older women: implications for etiology and treatment. J Gerontol A Biol Sci Med Sci. 2009 Oct;64(10):1049-57. Epub 2009 Jun 30. PMID: 19567825.

Hsiao CJ, Bandeen-Roche K, Marsteller JA, Leff BA. The effect of disability on personal quality of primary care received by older adults. Disabil Rehabil. 2009;31(22):1835-42. PMID: 19479548.

Leng SX, Hung W, Cappola AR, Yu Q, Xue QL, Fried LP. White Blood Cell Counts, Insulinlike Growth Factor-1 Levels, and Frailty in Community-Dwelling Older Women. J Gerontol A Biol Sci Med Sci. 2009 Apr;64(4):499-502. Epub 2009 Feb 27. PMID: 19251912.

Leng SX, Xue QL, Tian J, Huang Y, Yeh SH, Fried LP. Associations of neutrophil and monocyte counts with frailty in community-dwelling disabled older women: results from the Women's Health and Aging Studies I. Exp Gerontol. 2009 Aug;44(8):511-6. Epub 2009 May 18. PMID: 19457449.

Mielke MM, Kozauer NA, Chan KC, George M, Toroney J, Zerrate M, Bandeen-Roche K, Wang MC, Vanzijl P, Pekar JJ, Mori S, Lyketsos CG, Albert M. Regionally-specific diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease. Neuroimage. 2009 May 15;46(1):47-55. Epub 2009 Feb 5. PMID: 19457371.

Qu T, Yang H, Walston JD, Fedarko NS, Leng SX. Upregulated monocytic expression of CXC chemokine ligand 10 (CXCL-10) and its relationship with serum interleukin-6 levels in the syndrome of frailty. Cytokine. 2009 Jun;46(3):319-24. Epub 2009 Apr 1. PMID: 19342252.

Semba RD, Ferrucci L, Sun K, Beck J, Dalal M, Varadhan R, Walston J, Guralnik JM, Fried LP. Advanced glycation end products and their circulating receptors predict cardiovascular disease mortality in older community-dwelling women. Aging Clin Exp Res. 2009 Apr;21(2):182-90. PMID: 19448391.

Sourial N, Wolfson C, Bergman H, Zhu B, Karunananthan S, Quail J, Fletcher J, Weiss D, Bandeen-Roche K, Béland F. A correspondence analysis revealed frailty deficits aggregate and are multidimensional. J Clin Epidemiol. 2009 Oct 30. [Epub ahead of print]. PMID: 19880286.

Sourial N, Wolfson C, Zhu B, Quail J, Fletcher J, Karunananthan S, Bandeen-Roche K, Béland F, Bergman H. Correspondence analysis is a useful tool to uncover the relationships among categorical variables. J Clin Epidemiol. 2009 Nov 5. [Epub ahead of print]. PMID: 19896800.

Szanton, S.L., Allen JK, Seplaki, CL, Bandeen-Roche K, Fried LP. Allostatic Load and Frailty in the Women’s Health and Aging Studies. Biol Res Nurs. 2009 Jan;10(3):248-56. Epub 2008 Sep 30. PMID: 18829589.

Tan EJ, Rebok GW, Yu Q, Frangakis CE, Carlson MC, Wang T, Ricks M, Tanner EK, McGill S, Fried LP. The Long-Term Relationship Between High-Intensity Volunteering and Physical Activity in Older African American Women. J Gerontol B Psychol Sci Soc Sci. 2009 Mar;64(2):304-11. Epub 2009 Jan 29. PMID: 19181687.

Thorpe RJ Jr, Weiss C, Xue QL, Fried LP. Transitions among disability levels or death in African American and white older women. J Gerontol A Biol Sci Med Sci. 2009 Jun;64(6):670-4. Epub 2009 Feb 19. PMID: 19228790.

Varadhan R, Chaves PH, Lipsitz LA, Stein PK, Tian J, Windham BG, Berger RD, Fried LP. Frailty and Impaired Cardiac Autonomic Control: New Insights From Principal Components Aggregation of Traditional Heart Rate Variability Indices. J Gerontol A Biol Sci Med Sci. 2009 Jun;64(6):682-7. Epub 2009 Feb 17. PMID: 19223607.

Varadhan R, Gilbert P. BB: An R Package for Solving a Large System of Nonlinear Equations and for Optimizing a High-Dimensional Nonlinear Objective Function. J Stat Soft. 2009 Oct;32(4):1-26.

Walston JD, Matteini AM, Nievergelt C, Lange LA, Fallin DM, Barzilai N, Ziv E, Pawlikowska L, Kwok P, Cummings SR, Kooperberg C, Lacroix A, Tracy RP, Atzmon G, Lange EM, Reiner AP. Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults. Exp Gerontol. 2009 May;44(5):350-5. Epub 2009 Feb 26. PMID: 19249341.

Xue, Q-L, Bandeen-Roche K. Latent variable regression analysis with missing covariates. Koln, Germany: Lambert Academic Publishing AG& Co. KG; 2009.

2008

Carlson MC, Helms MJ, Steffens DC, Burke JR, Potter GG,Plassman BL. Mid-life Activity Predicts Risk of Alzheimer’s Disease in Older Male Twin Pairs.  Alzheimers Dement. 2008 Sep;4(5):324-31.PMID: 18790459.

Dayhoff-Brannigan M, Ferrucci L, Sun K, Fried LP, Walston J, Varadhan R, Guralnik JM, Semba RD. Oxidative protein damage is associated with elevated serum interleukin-6 levels among older moderately to severely disabled women living in the community. J Gerontol A Biol Sci Med Sci. 2008 Feb;63(2):179-83. PMID: 18314454

De Fanis U, Wang G, Fedarko N, Walston J, Casolaro V, and Leng SX. T-lymphocytes expressing CC chemokine receptor-5 are increased in frail older adults. J Am Geriatr Soc. 2008 May;56(5):904-8. Epub 2008 Apr 1. PMID: 18384587.

Espinoza SE, Guo H, Fedarko N, DeZern A, Fried LP, Xue QL, Leng S, Beamer B, Walston JD. Glutathione peroxidase enzyme activity in aging. J Gerontol A Biol Sci Med Sci. 2008 May;63(5):505-9. PMID: 18511755.

Evans WJ, Bhasin S, Cress C, Espeland MA, Ferrucci L, Fried LP, Gill G, Pahor M, Studenski S (Working Group on Functional Outcome Measures for Clinical Trials). Functional outcomes for clinical trials in frail older persons: time to be moving. J Gerontol A Biol Sci Med Sci. 2008 Feb;63(2):160-4. PMID: 18314451.

Matteini AM, Walston JD, Fallin MD, Bandeen-Roche K, Kao WHL, Semba RD, Allen RH, Guralnik J, Fried LP, Stabler SP. Markers of B-vitamin deficiency and frailty in older women. J Nutr Health Aging. 2008 May;12(5):303-8. PMID: 18443711.

Mielke MM, Xue QL, Zhou J, Chaves PH, Fried LP, Carlson MC. Baseline Serum Cholesterol Is Selectively Associated With Motor Speed and Not Rates of Cognitive Decline: The Women's Health and Aging Study II. J Gerontol A Biol Sci Med Sci. 2008 Jun;63(6):619-24.

Mielke MM, Bandaru VV, Haughey NJ, Rabins PV, Lyketsos CG, Carlson MC. Serum sphingomyelins and ceramides are early predictors of memory impairment. Neurobiol Aging. 2010 Jan;31(1):17-24. Epub 2008 May 5.PMID: 18455839.

Swihart BJ, Caffo B, Bandeen-Roche K, Punjabi NM. Characterizing sleep structure using the hypnogram. J Clin Sleep Med. 2008 Aug 15;4(4):349-55. PMID: 18763427.

Varadhan R, Seplaki CL, Xue QL, Bandeen-Roche K, Fried LP. Stimulus-response paradigm for characterizing the loss of resilience in homeostatic regulation associated with frailty. Mech Ageing Dev. 2008 Nov;129(11):666-70. Epub 2008 Sep 30.PMID: 18938195.

Varadhan R, Walston J, Cappola AR, Carlson MC, Wand GS, Fried LP. Higher Levels and Blunted Diurnal Variation of Cortisol in Frail Older Women. J Gerontol A Biol Sci Med Sci 2008 63: 190-195.

Varadhan R., Roland C. Simple and globally-convergent methods for accelerating the convergence of any EM algorithm. Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics, Finnish Statistical Society, Norwegian Statistical Association and Swedish Statistical Association, vol. 35(2), pages 335-353.

Walston J, Fedarko N, Yang H, Leng S, Beamer B, Espinoza S, Lipton A, Zheng H, Becker K. The physical and biological characterization of a frail mouse model. J Gerontol A Biol Sci Med Sci. 2008 Apr;63(4):391-8. PMID: 18426963.

Xue Q-L, Fried LP, Glass TA, Laffan AM, Chaves PHM. Life-space constriction, development of frailty, and the competing risk of mortality: the Women's Health And Aging Study I. Am J Epidemiol. 2008 Jan 15;167(2):240-8. Epub 2007 Sep 28. PMID: 17906296.

Xue Q-L, Bandeen-Roche K, Zhou J, Varadhan R, Fried LP. Initial manifestations of frailty criteria and the development of frailty phenotype in the Women’s Health and Aging Study II. J Gerontol A Biol Sci Med Sci. 2008 Sep;63(9):984-90.PMID: 18840805.

2007

Barzilay JI, Blaum C, Moore T, Xue Q-L, Hirsch CH, Walston JD, Fried LP. Insulin Resistance and Inflammation as Precursors of Frailty: The Cardiovascular Health Study. Arch Intern Med 2007; 167(7):635-41. PMID: 17420420.

Beck J, Ferrucci L, Sun K, Walston J, Fried LP, Varadhan R, Guralnik JM, Semba RD. Low serum selenium concentrations are associated with poor grip strength among older women living in the community. Biofactors. 2007;29(1):37-44. PMID: 17611292.

Boyd CM, Weiss CO, Halter J, Han KC, Ershler WB, Fried LP: Framework for Evaluating Disease Severity Measures in Older Adults with Comorbidity. J Gerontol A Biol Sci Med Sci. 2007, Vol. 62A, No. 3, 286–295. PMID: 17389726.

Chang DC, Joyce DL, Shoher A, Yuh DD. A Simple Index to Predict Likelihood of Skilled Nursing Facility Admission after CABG among Older Patients. Ann Thorac Surg. 2007 Sep;84(3):829-34; discussion 834-5. PMID: 17720384

Desquilbet L, Jacobson LP, Fried LP, Phair JP, Jamieson BD, Holloway M, Margolick JB; Multicenter AIDS Cohort Study. HIV-1 infection is associated with an earlier occurrence of a phenotype related to frailty. J Gerontol A Biol Sci Med Sci. 2007 Nov;62(11):1279-86. PMID: 18000149.

Folsom AR, Boland LL, Cushman M, Heckbert SR, Rosamond WD, Walston JD. Frailty and risk of venous thromboembolism in older adults. J Gerontol A Biol Sci Med Sci. 2007 Jan;62(1):79-82. PMID: 15066083.

Howard C, Ferrucci L, Sun K, Fried LP, Walston J, Varadhan R, Guralnik JM, Semba RD. Oxidative protein damage is associated with poor grip strength among older women living in the community. J Appl Physiol. 2007 Jul;103(1):17-20. Epub 2007 Mar 22. PMID: 17379753.

Leng SX, Xue Q-L, Tian J, Walston J, Fried LP. Inflammation and frailty in older women. J Am Geriatr Soc. 2007 Jun;55(6):864-71. PMID: 17537086.

Rebok GW, Carlson MC, & Langbaum JB. Training and maintaining memory abilities in healthy older adults: traditional and novel approaches. J Gerontol B Psychol Sci Soc Sci. 2007 Jun;62 Spec No 1:53-61. Review. PMID: 17565165.

Roland C., Varadhan R., and Frangakis C.E. Squared polynomial extrapolation methods with cycling: an application to the positron emission tomography problem, Numerical Algorithms, Volume 44, Number 2, February 2007, pp. 159-172.

Semba RD, Ferrucci L, Sun K, Walston J, Varadhan R, Guralnik JM, Fried LP. Oxidative stress and severe walking disability among older women. Am J Med. 2007 Dec;120(12):1084-9. PMID: 18060930.

Semba RD, Ricks MO, Ferrucci L, Xue QL, Guralnik JM, Fried LP. Low serum selenium is associated with anemia among older adults in the United States. Eur J Clin Nutr. 2007 Sep 5; [Epub ahead of print]. PMID: 17805227.

Walston JD, Fallin MD, Cushman M, Lange L, Psaty B, Jenny N, Browner W, Tracy R, Durda P, Reiner A. IL-6 gene variation is associated with IL-6 and C-reactive protein levels but not cardiovascular outcomes in the Cardiovascular Health Study. Hum Genet. 2007 Dec;122(5):485-94. Epub 2007 Sep 13. PMID: 17851695.

Weiss CO, Boyd CM, Yu Q, Wolff JL, Leff B. Patterns of prevalent major chronic disease among older adults in the United States. JAMA. 2007 Sep 12;298(10):1160-2. PMID: 17848649.

2006

Arking DE, Fallin DM, Li T, Beamer BA, Xue QL, Fried LP, Chakravarti A, Walston JD. Variation in the Ciliary Neurotrophic Factor Gene and Muscle Strength in Older Caucasian Women. Journal of the American Geriatrics Society, 2006; May;54(5):823-6. PMID: 16696750.

Bandeen-Roche K, Xue Q-L, Ferrucci L, Walston J, Guralnik JM, Chaves PHM, Zeger SL, Fried LP. Phenotype of Frailty: Characterization in the Women’s Health and Aging Studies. J Gerontol Med Sci, 2006 Mar;61(3):262-6. PMID: 16567375.

Bartali B, Frongillo EA, Bandinelli S, Lauretani F, Semba RD, Fried LP, Ferrucci L. Low nutrient intake is an essential component of frailty in older persons. J Gerontol: Med Sci. 2006 Jun;61(6):589-93. PMID: 16799141.

Chaves PHM, Carlson MC, Guralnik JM, Ferrucci L, Semba R, Fried LP. Association of Mild Anemia with Executive Cognitive Function Impairment in Community-Dwelling Older Women: The Women’s Health and Aging Study II. J Am Geriatr Soc. 2006 Sep;54(9):1429-35. PMID: 16970654.

Chi PB, Duggal P, Kao WH, Mathias RA, Grant AV, Stockton ML, Garcia JG, Ingersoll RG, Scott AF, Beaty TH, Barnes KC, Fallin MD. Comparison of SNP tagging methods using empirical data: association study of 713 SNPs on chromosome 12q14.3-12q24.21 for asthma and total serum IgE in an African Caribbean population. Genet Epidemiol. 2006 Nov: 30(7):609-19. PMID: 16830339.

Kim DH, Lipsitz LA, Ferrucci L, Guralnik JM, Carlson M, Fleisher LA, Fried LP, Chaves PHM. Association of Reduced Heart Rate Variability with Cognitive Impairment in Older Disabled Women in the Community: A Pilot Study in the Women’s Health and Aging Study I. J Am Geriatr Soc. 2006 Nov;54(11):1751-7. PMID: 17087704.

Ling SM, Xue QL, Simonsick EM, Tian J, Bandeen-Roche K, Fried LP, Bathon JM. Transitions to mobility difficulty associated with lower extremity osteoarthritis in high functioning older women: longitudinal data from the Women's Health and Aging Study II. Arthritis Rheum. 2006 Apr 15;55(2): 256-63. PMID: 16583416.

Michelon E, Blaum C, Semba RD, Xue QL, Ricks MO, Fried LP. Vitamin and carotenoid status in older women: associations with the frailty syndrome. J Gerontol A Biol Sci Med Sci. 2006 Jun;61(6):600-7. PMID: 16799143.

Studenski S, Carlson MC, Fillit H, Greenough WT, Kramer A, Rebok GW.. From bedside to bench: does mental and physical activity promote cognitive vitality in late life? Sci Aging Knowledge Environ 2006. 28; (10): 21. PMID: 16807485.

Tan EJ, Xue QL, Li T, Carlson MC, Fried LP. Volunteering: a physical activity intervention for older adults--The Experience Corps program in Baltimore.J Urban Health. 2006 Sep;83(5):954-69. PMID: 16763775.

Walston J, Hadley EC, Ferrucci L, Guralnik J, Newman, AB, Studenski S, Ershler W, Harris T, Fried LP. Research agenda for Frailty in Older Adults: Towards a Better Understanding of Physiology and Etiology. J Am Geriatr Soc. 2006 Jun;54(6):991-1001. PMID: 16776798.

Walston J, Xue Q-L, Semba RD, Ferrucci L, Cappola AR, Ricks M, Guralnik JM, Fried LP. Serum Antioxidants, Inflammation, and Mortality in Older Women. American Journal of Epidemiology 2006:Jan1;163(1):18-26. PMID: 16306311.

2005

Benke KS, Chase GA, Fallin D. Use of susceptibility scoring in conjunction with the genotypic transmission disequilibrium test. BMC Genet. 2005 Dec 30;6 Suppl 1:S137. PMID: 16451596

Blaum CS, Xue Q-L, Michelon E, Semba RD, Fried LP. The association of obesity and the frailty syndrome in older women. The Journal of the American Geriatrics Society 2005 June; 53(6):927-34. PMID: 15935013.

Boyd CM, Darer J, Boult C, Fried LP, Boult L, Wu A. Clinical Practice Guidelines and Quality of Care for Older Patients With Multiple Comorbid Diseases: Implications for Pay for Performance. JAMA, August 10, 2005:294:5:716-724. PMID: 16091574.

Boyd CM, Xue Q-L, Simpson CF, Guralnik JM, Fried LP. Frailty, hospitalization and progression of disability in a cohort of disabled older women: The Women’s Health and Aging Study I. The American Journal of Medicine, 2005 Nov;118(11):1225-31. PMID: 16271906.

Chaves PH, Semba RD, Leng SX, Woodman RC, Ferrucci L, Guralnik JM, Fried LP. Impact of Anemia and Cardiovascular Disease on Frailty Status of Community-Dwelling Older Women: The Women’s Health and Aging Studies I and II. J Gerontol Med Sci, 2005 June;60A:6:729-735. PMID: 15983175.

Fried LP, Hadley EC, Walston JD, Newman A, Guralnik JM, Studenski S, Harris TB, Ershler WB, Ferrucci L. From bedside to bench: research agenda for frailty. Sci Aging Knowledge Environ. 2005 Aug 3;2005(31):pe24. PMID: 16079413.

Leng SX, Xue Q-L, Huang Y, Ferrucci L, Beamer BA, Fried LP, Walston J. Baseline Total and Specific Differential White Blood Cell Counts and 5-year All-Cause Mortality in Community-Dwelling Older Women. Experimental Gerontology, 2005 Dec, (40):982-987. PMID: 16183235.

Leng SX, Xue Q-L, Huang Y, Semba R, Chaves P, Bandeen-Roche K, Fried LP, Walston J. Total and differential WBC counts and their associations with circulating IL-6 levels in community-dwelling older women. J Gerontol Med Sci, 2005;60A:195-199.

Nicodemus KK, Liu W, Chase GA, Tsai YY, Fallin MD. Comparison of type I Error for Multiple Test Corrections in Large SNP Studies Using Principal Components Versus Haplotype Blocking Algorithms. BMC Genetics 2005 Dec: 6 Suppl 1:S78. PMID: 16451692

Walston J, Arking DE, Fallin D, Li T, Beamer B, Xue Q, Ferrucci L, Fried LP, Chakravarti A. IL-6 Gene Variation is not Associated with Increased Serum Levels of IL-6, muscle weakness, or frailty in older women. Experimental Gerontology, 2005; 40:344-352. PMID: 15820616.

Wang C-P, Brown CH, Bandeen-Roche K. Residual Diagnostics for Growth Mixture Models: Examining the Impact of a Preventive Intervention on Multiple Trajectories of Aggressive Behavior. Journal of the American Statistical Association, 2005 Sep;100(3):1054-1076.

Yuh DD, Baumgartner WA. Cardiac Surgery in the Elderly. In: Gerstenblith G, ed. Cardiovascular Disease in the Elderly. Totowa, NJ, Humana Press, Inc. 2005 June: pp. 179-201.

2004

Bjornsson HT, Cui H, Guis D, Fallin MD, Feinberg AP. The New Field of Epigenomics: Implications for Cancer and Other Common Disease Research. Cold Spring Harb Symp Quant Biol. 2004: 69:447-56. PMID: 16117680.

Bjornsson HT, Fallin MD, Feinberg AP. An integrated epigenetic and genetic approach to common human disease. Trends Genet. 2004 Aug: 20(8):350-8. PMID: 15262407.

Ferrucci L, Guralnik JM, Studenski S, Fried LP, Cutler GB Jr, Walston JD (Interventions on Frailty Working Group). Designing randomized, controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: a consensus report. J Am Geriatr Soc. 2004 Apr;52(4):625-34. PMID: 15066083.

Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci. 2004 Mar;59(3):255-63. PMID: 15031310.

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OAIC NEWS

Dr. Reyhan Westbrook, OAIC Postdoctoral Fellow, awarded 1st prize at the 7th Annual Research on Aging Showcase in the Bloomberg School of Public Health (More)

OAIC-led symposium presented at the 2014 International Conference on Frailty and Sarcopenia Research in Barcelona (More)

OAIC Investigators identify multiple genetic loci significantly associated with inflammatory markers in older adults (More)

Dr. Walston receives 2013 Glenn Award for Research in Biological Mechanisms of Aging (More)

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