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Johns Hopkins Center on Aging and Health


JHU OAIC- sponsored Symposia at the 2012 Annual Meeting of the Gerontological Society of America

The Aging Renin-Angiotensin System and the Potential for Intervention
11/17/2012, 8 am to 9:30 am
Jeremy Walston – Chair
Peter Abadir – Co-chair
Kevin High – Discussant
Peter Abadir:  Regulation of mitochondrial biogenesis with Losartan in the heart of 150 wks old aged mice.

Tyesha Burks:  Age-dependent Effects of Angiotensin II Type I Receptor Blockade on Disuse Atrophy.

Ashwin Akki: Losartan Improves Aging-Associated Decline in Myocardial Energy Metabolism.

Sevil Yasar: The Renin Angiotensin System (RAS) and Physical Function.

The IL-10-/- Frail Mouse as a Model for Age-Related Disease States
11/16/2012, 8 am to 9:30 am
Jeremy Walston – Chair
Laura Dugan – Discussant
W. Nguyen: Behavioral assessment of the IL-10-/- mouse model of frailty suggests impairments in emotional learning and anxiety response to environment.

Laura Dugan: Progressive increases in brain inflammatory superoxide predict region-specific deficits in critical inhibitory interneurons in IL-10-/- mice.

Ashwin Akki: Skeletal Muscle Creatine Kinase ATP Kinetics are Impaired in Frail Mice.

Gautam Sikka: IL10-/- Frail Mice Develop Cardiac and Vascular Dysfunction with Increased Age.

For more information, please click here to visit the Gerontological Society of America's 2012 Annual Meeting website

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